The College of Business in Khulais started with a Management Information Systems division within the Computer Science and Information Technology Department at the College of Sciences and Arts in Khulais, one of the branches of King Abdulaziz University. Teaching began at the start of the 1430/1431 AH academic year (which corresponds to 2009/2010 AD). The Higher Education Council's decision No. 28/66/1432, issued in 1432 AH (2011 AD), restructured the College of Sciences and Arts in Khulais into three colleges, one of which is the Business School in Khulais. The college includes three active academic departments: the Management Information Systems Department, the Human Resources Management Department, and the Management of Health Services and Hospital Department.