The College of Business in Khulais was established in 1432 AH after the issuance of Royal Decree No. 54727 dated 11/18/1432 and the issuance of Higher Education Council Resolution No. 28/66/1432 in 1432 AH to provide higher education in various business administration branches to qualify male and female students for the job market. The college seeks to provide the best scientific programs in the field of business while providing students with the functional skills required in the work environment that enable them to achieve a local and regional competitive advantage and achieve harmony between the outcomes of the educational process and the needs of the labor market within the framework of the quality requirements required for the graduate. In addition to deepening scientific research in various specializations in a way that contributes to serving the community.

The college includes seven scientific departments: the Department of Management Information Systems, the Department of Human Resources Management, the Department of Accounting, the Department of Finance, the Department of Marketing, the Department of Management of Health Services and Hospitals, and the Department of Law. Three of them have been activated: the Management Information Systems Department, the Human Resources Management Department, and the Management of Health Services and Hospitals Department.